3D-QSAR study for novel inhibitors of mitogen activated protein kinase-activated protein kinase 2
Protein kinase Cε and β cell secretion funtion
ObjectiveTo assess the clinical significance of detection of serum creatine kinase (CK), creatine kinase (CK-MB), lactate dehydrogenase (LD), and aspartate aminotransferase (AST) in psychotics.
Effect of interleukin-1 receptor associated kinase-M on lipopolysaccharide pretreatment relieving chronic liver injury
Screening of potential small-molecular inhibitor of human Aurora-B kinase using budding yeast
The content of water and MDA in myocardium and creatin kinase (CK) in the coronary effluent were measured.
Objective to investigate effects of PDGF on phenotypic change of glomerular mesangial cells (MC), and study intracellular mechanisms through mitogen-activated - protein kinase (MAPK) pathways.
After 24 hours, blood was collected to examine serum free T3, free t, TSH, isoenzyme of creatine kinase (CK-MB) and levels of portal vein blood endotoxin.
Therefore, the aim of this study is to investigate the effects of genistein, a protein tyrosine kinase inhibitor, on acute and chronic inflammation in diabetic mice (induced by streptozotocin).
Advances in relationship Between Rho-kinase Inhibitors and Heart Failure
The kinase transfers the phosphate from an autophosphorylated histidine and thus (why thus?) is often reversible, with the kinase acting as a phosphatase as well.
The soft-tissue injury was assessed by measuring serum creatine kinase.
Expression and role of p38 mitogen-activated protein kinase in hyperoxia-induced lung injury juvenile rat model
There was no significant increase in liver and renal function and concentration of creatine kinase after treatment in these two groups.
Objective To discuss the relationship between estradiol and the mitogenic activated protein kinase signal transduction pathway and the expression of the MAPK in the MCF-7 breast cancer cell-line.
Advances in the research of multi-target tyrosine kinase inhibitors
Targeted activation of protein kinase PKR induced apoptosis of leukemia K562 cells
Hirudin attenuates sequestration of neutrophils and expression of Rho kinase in lung tissue of ALI mice induced by LPS
Objective To study the expression of thymidine kinase (TK) and proliferating cell nuclear antigen (PCNA) in hydatidiform mole and assess their prognostic value.
Updated correlation of the protein kinase C family with cancer
Objective to investigate the effect of mitogen-activated protein kinase (MAPK) on pathogenesis in myocardium hypertrophy of renal hypertension rats.
The anticancer role of aurora kinase inhibitors
The irreversible inhibition of creatine kinase from human muscle during modification with DTNB has been studied.
Multi-targeted protein tyrosine kinase inhibitor:research advances
Effects of fluvastatin on the activation of p38 mitogen-activated protein kinase in glomerular mesangial cells under high concentration of glucose
Role of membrane-type matrix metalloproteinase-1 in apoptosis of hepatic stellate cell induced by focal adhesion kinase-related non-kinase in vitro
Objective To observed the influence of luteolin on protein kinase C activity in human leukemic cells (HL-60).
