Clinical Phenotype of HNPCC Syndrome and Quick Screening Platform and Predictive Role in Cancer Risk of Minor Mutation of Mismatch Repair Genes in China;
Cumulative Cancer Risk of hMLH1and hMSH2 Germline Mutation Carriers in HNPCC Families
目的：分析*人遗传*非息肉病*大肠癌(HNPCC)家系的临床特征并检测这些家系中M3胆碱能受体基因(A)8区的突变情况。
Age at diagnosis of HNPCC ranged from 26 to 74 years,the median age was 53.4 years.
Objective: to characterize the clinical features of Chinese HNPCC families and to screen the mutations of a poly (a) 8 tract in M3 cholinergic receptor gene in these families.
